Introduction:Selecting education methods can help Instructors to use methods that are more effective for future nursing Programs. The aim of this study was to compare the effect of CD-based and traditional education on Nursing Students’ learning in Tehran University of medical sciences.

Methods: In this quasi-experimental study two case and control groups were selected. 38 nursing students (19 students in each group) who were passing community health nursing course 3 in 2012-2013 were divided equally into two groups of CD-based education and traditional education by using random allocation method. In the case group, the intervention consisted of delivering educational material using compact disc for 8 weeks. The other group received educational material by lecturing in the classroom at the same time. In both groups, final exam scores measured students’ learning 3 weeks after finishing the course. Two groups’ scores were compared by descriptive statistic as mean, standard deviation, independent T test, k square and Analysis of Covariance (Ancova) using spss version 16.

 Results: Based on the findings, mean and standard deviation of final exam scores in the case and control groups were M=13.70± 1.80 and 13.41 ± 1.85. Analysis of Covariance (ANCOVA) test showed that Compact Disc -based education and traditional education had the same effect on the Nursing Students’ Learning (p value: 0.55).

Conclusions: According to the finding, Compact Disc -based education seems to be as effective as traditional education on the Nursing Students’ Learning. Therefore, with regard to the advantages of modern educational methods, it is recommended to be used in the blended method of educational programs.