Introduction: Professional socialization of nurses is essential in this caring profession and has a direct link with the quality of provided services. This study has been conducted with the aim of investigating the barriers of the socialization in nurses and provide strategies to address these barriers. Method: This integrative review conducted based on the Broome approach. The studies that related to the purpose of study, being written in English or Persian, the full text was accessible and were published in the last 10 years, entered into research. Articles without name, no date and non-scientific were excluded. A wide range of Keywords such as Professional Socialization, Nursing, Nurse was used to retrieve related studies. Besides studying library, Persian and International accredited online databases such as Magiran, SID, Iranmedex, Pubmed, google scholar, MEDLINE, Scopus, Elsevier and Sciencedirect were used. Ultimately, 21 articles were included. Data were analyzed based on Broom's method. Results: Analysis results showed that professional socialization of nurses' barriers consist of three main categories of professional factors, economic- welfare facilities factors and social factors. Conclusion: It's impossible to provide desirable and quality care by nurses without considering their social status and promoting it. So, health care system needs to consider professional, economic and social barriers and apply the necessary measures to eliminate these barriers in order to improve the quality of care and patient satisfaction.