Introduction: Clinical training is one of the main components in nursing students programs. The lack of clinical skills during academic study providing of nursing care with quality will be difficult for future job in nursing students. Due to Clinical Teaching Partner Model is known as clinical training pattern this study aimed to evaluate the effectiveness of Clinical Teaching Partner Model on clinical skills in nursing students of Bushehr University of Medical Sciences. Method: This is a quasi-experimental study. Forty five of fifth semester nursing students were intervene by Census under two different clinical teaching methods on the Persian Gulf Martyrs Hospital of Bushehr in 1394. Forty five nursing students by simple random allocation assigned to two groups as control (n = 22) and test (n = 23) groups. Before and after the training period, students' clinical skills evaluated with a questionnaire. Face and content validity of the questionnaire were assessed. In order to analyze the data, descriptive and inferential statistics such as: chi square test, Fisher exact test, Mann-Whitney U, variance t test was performed by using software spss.ver18. Findings: Between the experimental and control groups in terms of clinical skills in the areas of duties of circular nurse, duties of recovery nurse, infection control and sterilization there was a significant difference(p<0/05). Between the experimental and control groups in terms of duties of circular nurse was not significant difference (p=0/058). Conclusion: Due to the increased skills of nursing students in Clinical Teaching Partner Model in this study, it is concluded this model is an appropriate method for clinical training to nursing students. Accordingly, the use of Clinical Teaching Partner Model in order to more benefit the experience, Constant presence alongside students and Practical knowledge of nurses in every ward is recommended for skills training to nursing students.